Detalhe da pesquisa
1.
Potent transmission-blocking monoclonal antibodies from naturally exposed individuals target a conserved epitope on Plasmodium falciparum Pfs230.
Immunity
; 56(2): 420-432.e7, 2023 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36792575
2.
Highly potent, naturally acquired human monoclonal antibodies against Pfs48/45 block Plasmodium falciparum transmission to mosquitoes.
Immunity
; 56(2): 406-419.e7, 2023 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36792574
3.
Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses.
Immunity
; 55(9): 1680-1692.e8, 2022 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35977542
4.
Immunity against sexual stage Plasmodium falciparum and Plasmodium vivax parasites.
Immunol Rev
; 293(1): 190-215, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31840844
5.
Modeling the Impact of a Highly Potent Plasmodium falciparum Transmission-Blocking Monoclonal Antibody in Areas of Seasonal Malaria Transmission.
J Infect Dis
; 228(2): 212-223, 2023 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37042518
6.
An inhibitor of complement C5 provides structural insights into activation.
Proc Natl Acad Sci U S A
; 117(1): 362-370, 2020 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31871188
7.
The CRISPRs, they are a-changin': how prokaryotes generate adaptive immunity.
Annu Rev Genet
; 46: 311-39, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23145983
8.
DNA-guided DNA interference by a prokaryotic Argonaute.
Nature
; 507(7491): 258-261, 2014 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24531762
9.
CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3.
Mol Cell
; 46(5): 595-605, 2012 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22521689
10.
Structures of the RNA-guided surveillance complex from a bacterial immune system.
Nature
; 477(7365): 486-489, 2011 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21938068
11.
Native tandem and ion mobility mass spectrometry highlight structural and modular similarities in clustered-regularly-interspaced shot-palindromic-repeats (CRISPR)-associated protein complexes from Escherichia coli and Pseudomonas aeruginosa.
Mol Cell Proteomics
; 11(11): 1430-41, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22918228
12.
Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence.
Proc Natl Acad Sci U S A
; 108(25): 10098-103, 2011 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21646539
13.
CRISPR-based adaptive and heritable immunity in prokaryotes.
Trends Biochem Sci
; 34(8): 401-7, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19646880
14.
Clinical formulation development of Plasmodium falciparum malaria vaccine candidates based on Pfs48/45, Pfs230, and PfCSP.
Vaccine
; 42(8): 1980-1992, 2024 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38388238
15.
Target-agnostic identification of human antibodies to Plasmodium falciparum sexual forms reveals cross stage recognition of glutamate-rich repeats.
bioRxiv
; 2023 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37961136
16.
Pfs230 Domain 7 is targeted by a potent malaria transmission-blocking monoclonal antibody.
NPJ Vaccines
; 8(1): 186, 2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38086855
17.
Deceiving and escaping complement - the evasive journey of the malaria parasite.
Trends Parasitol
; 38(11): 962-974, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36089499
18.
Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun
; 13(1): 317, 2022 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35031611
19.
Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.
Nat Commun
; 13(1): 5603, 2022 09 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36153317
20.
Heterologous Expression and Evaluation of Novel Plasmodium falciparum Transmission Blocking Vaccine Candidates.
Front Immunol
; 13: 909060, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35812379